Common Side Effects (2025)

Kernel Score: 89% · 249 ratings

Genres: Animation, Drama, Comedy, Sci-Fi & Fantasy

First aired: 2025-02-02

Seasons: 2 · 10 episodes

Where to watch Common Side Effects

  • Stream: YouTube TV, Adult Swim, HBO Max
  • Free with ads: Adult Swim
  • Buy: Prime Video, Apple TV, Google Play, Fandango At Home

US availability, updated 2026-10-22.

Overview

Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.

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Cast

  • Dave King as Marshall Cuso (voice)
  • Emily Pendergast as Frances Applewhite (voice)
  • Mike Judge as Rick Kruger (voice)
  • Martha Kelly as Agent Harrington (voice)
  • Joseph Lee Anderson as Agent Copano (voice)

Common Side Effects FAQ

Is Common Side Effects good?

Common Side Effects has an 89% Kernel Score on Fresh Kernels from 249 audience ratings.

Where can I watch Common Side Effects?

In the US you can stream Common Side Effects on YouTube TV, Adult Swim and HBO Max, watch it free with ads on Adult Swim and buy it from Prime Video, Apple TV, Google Play and Fandango At Home.

What is Common Side Effects rated?

Common Side Effects is rated TV-MA.

What shows are like Common Side Effects?

If you liked Common Side Effects, try Lazarus, Solar Opposites, Cyberpunk: Edgerunners and Inside Job.